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Sildenafil Versus Placebo for Early Pulmonary Vascular Disease in Scleroderma (SEPVADIS): protocol for a randomized controlled trial

Abstract Background Pulmonary hypertension (PH) is a leading cause of death in patients with systemic sclerosis (SSc). An important component of SSc patient management is early detection and treatment of PH. Recently the threshold for the diagnosis of PH has been lowered to a mean pulmonary artery p...

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Hlavní autoři: Matthew R. Lammi, Monica Mukherjee, Lesley Ann Saketkoo, Kyle Carey, Laura Hummers, Steven Hsu, Amita Krishnan, Marie Sandi, Ami A. Shah, Stefan L. Zimmerman, Paul M. Hassoun, Steven C. Mathai
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2024-04-01
Edice:BMC Pulmonary Medicine
Témata:
Pulmonary hypertension
Scleroderma
Systemic sclerosis
Clinical trial
Sildenafil
On-line přístup:https://doi.org/10.1186/s12890-024-02892-3
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