Glucagon Potentiates Insulin Secretion Via β-Cell GCGR at Physiological Concentrations of Glucose

Incretin-potentiated glucose-stimulated insulin secretion (GSIS) is critical to maintaining euglycemia, of which GLP-1 receptor (GLP-1R) on β-cells plays an indispensable role. Recently, α-cell-derived glucagon but not intestine-derived GLP-1 has been proposed as the critical hormone that potentiate...

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Bibliografische gegevens

Hoofdauteurs:	Yulin Zhang, Chengsheng Han, Wenzhen Zhu, Guoyi Yang, Xiaohong Peng, Sohum Mehta, Jin Zhang, Liangyi Chen, Yanmei Liu
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	MDPI AG 2021-09-01
Reeks:	Cells
Onderwerpen:	glucagon GCGR GLP-1R α-cells β-cells glucose-stimulated insulin secretion
Online toegang:	https://www.mdpi.com/2073-4409/10/9/2495
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