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Neutralizing Antibodies Induced by Gene-Based Hydrodynamic Injection Have a Therapeutic Effect in Lethal Influenza Infection

The influenza virus causes annual epidemics and occasional pandemics and is thus a major public health problem. Development of vaccines and antiviral drugs is essential for controlling influenza virus infection. We previously demonstrated the use of vectored immune-prophylaxis against influenza viru...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Tatsuya Yamazaki, Maria Nagashima, Daisuke Ninomiya, Akira Ainai, Akira Fujimoto, Isao Ichimonji, Hidekazu Takagi, Naoko Morita, Kenta Murotani, Hideki Hasegawa, Joe Chiba, Sachiko Akashi-Takamura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018-01-01
Schriftenreihe:Frontiers in Immunology
Schlagworte:
passive immunotherapy
neutralizing antibody
gene therapy
hydrodynamics procedure
influenza
hemagglutinin
Online-Zugang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00047/full
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