Evaluation of a Conformationally Constrained Indole Carboxamide as a Potential Efflux Pump Inhibitor in <i>Pseudomonas</i> <i>aeruginosa</i>

Efflux pumps in Gram-negative bacteria such as <i>Pseudomonas aeruginosa</i> provide intrinsic antimicrobial resistance by facilitating the extrusion of a wide range of antimicrobials. Approaches for combating efflux-mediated multidrug resistance involve, in part, developing indirect antimicrobial a...

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Autori principali:	Yongzheng Zhang, Jesus D. Rosado-Lugo, Pratik Datta, Yangsheng Sun, Yanlu Cao, Anamika Banerjee, Yi Yuan, Ajit K. Parhi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-05-01
Serie:	Antibiotics
Soggetti:	<i>Pseudomonas aeruginosa</i> RND efflux pumps antimicrobial drug resistance efflux pump inhibitor indole carboxamide
Accesso online:	https://www.mdpi.com/2079-6382/11/6/716
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