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Structural and functional diversity of toxin-antitoxin-chaperone systems

Summary: Toxin-antitoxin-chaperone (TAC) systems are three-part gene clusters encoding a toxin, antitoxin, and specialized SecB-like chaperone (SecBTA) with emerging roles in phage defense. To identify and classify SecB homologs and associated TACs across bacteria, we surveyed the full RefSeq databa...

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Auteurs principaux: Jose A. Nakamoto, Roni Odai, Toomas Mets, Tanel Tenson, Tatsuaki Kurata, Vasili Hauryliuk, Gemma C. Atkinson
Format: Artigo
Langue:Inglês
Publié: Elsevier 2026-03-01
Collection:Cell Reports
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2211124726001026
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