Riluzole Reverses Blood–Testis Barrier Loss to Rescue Chemotherapy–Induced Male Infertility by Binding to TRPC

Cancer treatments, including cytotoxic therapy, often result in male infertility, necessitating the development of safe and effective strategies to preserve male reproductive potential during chemotherapy. Notably, our study uncovers the potential of repurposing riluzole, an FDA-approved drug for am...

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Prif Awduron:	Rufei Huang, Huan Xia, Wanqing Lin, Zhaoyang Wang, Lu Li, Jingxian Deng, Tao Ye, Ziyi Li, Yan Yang, Yadong Huang
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2024-12-01
Cyfres:	Cells
Pynciau:	riluzole male infertility spermatogenesis Sertoli cells blood–testis barrier TRPC5
Mynediad Ar-lein:	https://www.mdpi.com/2073-4409/13/23/2016
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!