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Of Murines and Humans: Modeling Persistent Powassan Disease in C57BL/6 Mice

ABSTRACT Powassan infection is caused by two closely related, tick-transmitted viruses of the genus Flavivirus (family Flaviviridae): Powassan virus lineage I (POWV) and lineage II (known as deer tick virus [DTV]). Infection is typically asymptomatic or mild but can progress to neuroinvasive disease...

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Principais autores: Stacey L. P. Scroggs, Danielle K. Offerdahl, Philip E. Stewart, Carl Shaia, Amanda J. Griffin, Marshall E. Bloom
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2023-04-01
Serier:mBio
Fag:
tick-borne infection
flavivirus
Powassan virus
deer tick virus
chronic
animal model
Online adgang:https://journals.asm.org/doi/10.1128/mbio.03606-22
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