Reduction of elevated Gli3 does not alter the progression of autosomal recessive polycystic kidney disease

Abstract Polycystic kidney diseases (PKD) are genetic disorders which disrupt kidney architecture and function. Autosomal recessive PKD (ARPKD) is a rare form of PKD, caused by mutations in PKHD1, and clinically more severe than the more common autosomal dominant PKD (ADPKD). Prior studies have impl...

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Bibliografiske detaljer

Principais autores:	Lauren G. Russell, Maria Kolatsi‐Joannou, Laura Wilson, Jennifer C. Chandler, Nuria Perretta Tejedor, Georgie Stagg, Karen L. Price, Christopher J. Rowan, Tessa Crompton, Norman D. Rosenblum, Paul J. D. Winyard, David A. Long
Format:	Artigo
Sprog:	Inglês
Udgivet:	Wiley 2025-01-01
Serier:	Physiological Reports
Fag:	autosomal recessive polycystic kidney disease cystogenesis hedgehog signaling human model mouse model
Online adgang:	https://doi.org/10.14814/phy2.70191
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