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A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila.

In polarized epithelial cells, receptor-ligand interactions can be restricted by different spatial distributions of the 2 interacting components, giving rise to an underappreciated layer of regulatory complexity. We explored whether such regulation occurs in the Drosophila wing disc, an epithelial t...

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Autori principali: Aidan J Peterson, Stephen J Murphy, Melinda G Mundt, MaryJane Shimell, Edward B Leof, Michael B O'Connor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2022-05-01
Serie:PLoS Biology
Accesso online:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001660&type=printable
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