Comprehensive multiomics profiling reveals the protective function of gypenosides against dextran sulfate sodium-induced colitis

Abstract In this study, we determined whether gypenosides exert a therapeutic effect on colitis. We then explored the underlying mechanism of gypenosides in the treatment of ulcerative colitis (UC) via multiomics analyses. Dextran sulfate sodium (DSS) was used to establish a UC model in mice, and a...

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Detalhes bibliográficos

Principais autores:	Yuan Yang, Xinyuan Li, Fan Huang, Fuchao Cai, Xufeng Ning, Qilin Jiang, Lingshan Zhou, Bin Zeng, Weiwei Zhou, Guangsheng Hu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2025-08-01
coleção:	Scientific Reports
Assuntos:	Gypenosides Colitis Metabolomics Transcriptome Stemness
Acesso em linha:	https://doi.org/10.1038/s41598-025-11010-0
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