Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin.

<h4>Background</h4>Proteinuria is a major marker of the decline of renal function and an important risk factor of coronary heart disease. Elevated proteinuria is associated to the disruption of slit-diaphragm and loss of podocyte foot processes, structural alterations that are considered irreversibl...

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Hlavní autoři:	Anne-Cécile Huby, Maria-Pia Rastaldi, Kathleen Caron, Oliver Smithies, Jean-Claude Dussaule, Christos Chatziantoniou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2009-08-01
Edice:	PLoS ONE
On-line přístup:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0006721&type=printable
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