Imbalanced IL10/TGF-β production by regulatory T-lymphocytes in patients with HTLV-1-associated myelopathy/ tropical spastic paraparesis

Abstract Background Human T-cell lymphotropic virus type 1 (HTLV-1), also denominated Human T-cell leukemia virus-1, induces immune activation and secretion of proinflammatory cytokines, especially in individuals with HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Regulatory T...

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Autori principali:	Luana Leandro Gois, Bárbara Ribeiro-Soares, Carlos Gustavo Regis-Silva, Dalila L Zanette, Raphaella Lisboa, Regina Santos Nascimento, Raimundo Coutinho Junior, Bernardo Galvão-Castro, Maria Fernanda Rios Grassi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-06-01
Serie:	BMC Infectious Diseases
Soggetti:	HTLV-1 Regulatory T lymphocytes IL10 TGF-β HTLV-associated myelopathy
Accesso online:	https://doi.org/10.1186/s12879-024-09494-8
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