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A single-molecule view of telomerase regulation at telomeres

Telomerase plays a key role in the immortalization of cancer cells by maintaining telomeres length. Using single-molecule imaging of telomerase RNA molecules in cancer cells, we recently reported novel insights into the role of Cajal bodies in telomerase biogenesis and the regulation of telomerase r...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Pascal Chartrand, Agnel Sfeir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis Group 2020-11-01
Schriftenreihe:Molecular & Cellular Oncology
Schlagworte:
Online-Zugang:http://dx.doi.org/10.1080/23723556.2020.1818537
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