Reduced GLP-1 response to a meal is associated with the CTLA4 rs3087243 G/G genotype

Although insulitis is the characteristic main feature of type 1 diabetes mellitus (T1DM), many aspects of β cell loss still remain elusive. Immune dysregulation and alterations in the dipeptidyl-peptidase-4-incretin system might have a role in disease development, but their connection is poorly unde...

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Detalhes bibliográficos

Principais autores:	András Zóka, Gábor Barna, Gábor Nyírő, Ágnes Molnár, László Németh, Györgyi Műzes, Anikó Somogyi, Gábor Firneisz
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Termedia Publishing House 2019-09-01
coleção:	Central European Journal of Immunology
Assuntos:	type 1 diabetes glp-1 autoimmune ctla4 incretin response genetic association study snps genetic susceptibility
Acesso em linha:	https://www.termedia.pl/Reduced-GLP-1-response-to-a-meal-is-associated-with-the-CTLA4-rs3087243-G-G-genotype,10,38543,1,1.html
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