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Molecular analysis of rpoB gene mutations in rifampicin resistant Mycobacterium tuberculosis isolates by multiple allele specific polymerase chain reaction in Puducherry, South India

Summary: Background: rpoB gene mutations in Mycobacterium tuberculosis (MTB) make the bacteria resistant to rifampicin. Thus, these mutations are surrogate markers for multi-drug resistance (MDR). The objective of this study was to evaluate an allele-specific multiplex-polymerase chain reaction (MA...

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Principais autores: Ravibalan Thirumurugan, Maruthai Kathirvel, Kommoju Vallayyachari, Kesavan Surendar, Antony V. Samrot, Muthuraj Muthaiah
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015-11-01
Serija:Journal of Infection and Public Health
Online dostop:http://www.sciencedirect.com/science/article/pii/S1876034115001008
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