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Comparative evaluation of MPTP and rotenone as inducing agents for Parkinson's disease in adult zebrafish: Behavioural and histopathological insights

Parkinson's disease (PD), a prevalent neurodegenerative disorder, is marked by dopaminergic neuron loss and motor impairments. This study aimed to establish and compare PD models in adult zebrafish using two neurotoxins, MPTP and rotenone, evaluating their impact on behaviour and histopathology. Zeb...

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Principais autores: Chetan Ashok, Naveen Kumar Rajasekaran, Srikanth Jeyabalan, Gayathri Veeraraghavan, Subalakshmi Suresh, Ramya Sugumar, Sugin Lal Jabaris, Vetriselvan Subramaniyan, Ling Shing Wong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2025-12-01
coleção:Toxicology Reports
Assuntos:
Zebrafish
Parkinson’s disease
MPTP
Rotenone
Behavioural analysis
Histopathology
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2214750025002021
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