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Cancer associated fibroblasts in cancer development and therapy

Abstract Cancer-associated fibroblasts (CAFs) are key players in cancer development and therapy, and they exhibit multifaceted roles in the tumor microenvironment (TME). From their diverse cellular origins, CAFs undergo phenotypic and functional transformation upon interacting with tumor cells and t...

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Bibliografische Detailangaben
Hauptverfasser: Hongyuan Jia, Xingmin Chen, Linling Zhang, Meihua Chen
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-03-01
Schriftenreihe:Journal of Hematology & Oncology
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Online-Zugang:https://doi.org/10.1186/s13045-025-01688-0
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