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A same‐day assay predicts apoptotic response to combined BCL‐2 and MCL‐1 BH3‐mimetic targeting in multiple myeloma cells

Abstract Recent advances in treatment options for multiple myeloma (MM) have positive impact on patient survival. However, there is a short fall of rapid and reliable assays that can predict patient response to novel agents. The anti‐apoptotic proteins B‐cell lymphoma‐2 (BCL‐2) and myeloid cell leuk...

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Hlavní autoři: Martin Grundy, Firas Al‐Kaisi, Joanna Cull, Cathy Williams, Dean Smith, Claire H. Seedhouse
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2021-02-01
Edice:eJHaem
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On-line přístup:https://doi.org/10.1002/jha2.133
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