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Intradermal electroporation of naked replicon RNA elicits strong immune responses.

RNA-based vaccines represent an interesting immunization modality, but suffer from poor stability and a lack of efficient and clinically feasible delivery technologies. This study evaluates the immunogenic potential of naked in vitro transcribed Semliki Forest virus replicon RNA (RREP) delivered int...

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Bibliografische Detailangaben
Hauptverfasser: Daniel X Johansson, Karl Ljungberg, Maria Kakoulidou, Peter Liljeström
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3251598?pdf=render
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