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Canonical Wnt signaling induces focal adhesion and Integrin beta-1 endocytosis

Summary: During canonical Wnt signaling, the Wnt receptor complex is sequestered together with glycogen synthase kinase 3 (GSK3) and Axin inside late endosomes, known as multivesicular bodies (MVBs). Here, we present experiments showing that Wnt causes the endocytosis of focal adhesion (FA) proteins...

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Bibliografske podrobnosti
Principais autores: Nydia Tejeda-Muñoz, Marco Morselli, Yuki Moriyama, Pooja Sheladiya, Matteo Pellegrini, Edward M. De Robertis
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2022-04-01
Serija:iScience
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Online dostop:http://www.sciencedirect.com/science/article/pii/S2589004222003935
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