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A Phase I Randomized Trial of Topical Insulin for Glaucoma: Safety and Efficacy Outcomes

Purpose: Insulin is neuroprotective in mouse and nonhuman primate models of glaucoma. Here we evaluate the safety and efficacy of topical insulin in human patients with glaucoma. Methods: This prospective study of once-daily topical insulin for glaucoma was conducted in 2 parts: an open-label dose e...

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Autors principals: Mariella Saludares, Zachary Wennberg-Smith, Gala Beykin, MD, Tasneem Z. Khatib, MD, PhD, Mariana Nunez, MD, QianQian Wang, MD, Adriana Di Polo, PhD, Jeffrey L. Goldberg, MD, PhD
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2026-02-01
Col·lecció:Ophthalmology Science
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S2666914525003306
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