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Characterization of aging cancer-associated fibroblasts draws implications in prognosis and immunotherapy response in low-grade gliomas

Background: Due to the highly variable prognosis of low-grade gliomas (LGGs), it is important to find robust biomarkers for predicting clinical outcomes. Aging cancer-associated fibroblasts (CAFs) within the senescent stroma of a tumor microenvironment (TME) have been recently reported to play a key...

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Principais autores: Zijian Zhou, Jinhong Wei, Lijun Kuang, Ke Zhang, Yini Liu, Zhongming He, Luo Li, Bin Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-08-01
coleção:Frontiers in Genetics
Assuntos:
low-grade glioma
aging cancer-associated fibroblasts
tumor microenvironment
prognosis
immunotherapy response
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fgene.2022.897083/full
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