Safety, tolerability, pharmacodynamic and wellbeing effects of SPL026 (dimethyltryptamine fumarate) in healthy participants: a randomized, placebo-controlled phase 1 trial

BackgroundDue to their potential impact on mood and wellbeing there has been increasing interest in the potential of serotonergic psychedelics such as N,N-dimethyltryptamine (DMT) in the treatment of major depressive disorder (MDD).AimThe aim of Part A of this study was to evaluate the safety, toler...

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Үндсэн зохиолчид:	Ellen James, David Erritzoe, Tiffanie Benway, Zelah Joel, Christopher Timmermann, Meghan Good, Claudio Agnorelli, Brandon M. Weiss, Tommaso Barba, Graham Campbell, Michelle Baker Jones, Charlotte Hughes, Helen Topping, Malcolm Boyce, Carol Routledge
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-01-01
Цуврал:	Frontiers in Psychiatry
Нөхцлүүд:	dimethyltryptamine major depressive disorder pharmacodynamic psychedelic safety tolerability
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fpsyt.2023.1305796/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!