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Global changes in the rat heart proteome induced by prolonged morphine treatment and withdrawal.

Morphine belongs among the most commonly used opioids in medical practice due to its strong analgesic effects. However, sustained administration of morphine leads to the development of tolerance and dependence and may cause long-lasting alterations in nervous tissue. Although proteomic approaches en...

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Detalhes bibliográficos
Principais autores: Zdenka Drastichova, Jitka Skrabalova, Petr Jedelsky, Jan Neckar, Frantisek Kolar, Jiri Novotny
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3467212?pdf=render
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