Neural xenografts contribute to long-term recovery in stroke via molecular graft-host crosstalk

Abstract Stroke remains a leading cause of disability due to the brain’s limited ability to regenerate damaged neural circuits. Here, we show that local transplantation of iPSC-derived neural progenitor cells (NPCs) improves brain repair and long-term functional recovery in stroke-injured mice. NPCs...

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Bibliografiske detaljer

Principais autores:	Rebecca Z. Weber, Beatriz Achón Buil, Nora H. Rentsch, Patrick Perron, Stefanie Halliday, Allison Bosworth, Mingzi Zhang, Kassandra Kisler, Chantal Bodenmann, Kathrin J. Zürcher, Daniela Uhr, Debora Meier, Siri L. Peter, Melanie Generali, Shuo Lin, Markus A. Rüegg, Roger M. Nitsch, Christian Tackenberg, Ruslan Rust
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Portfolio 2025-09-01
Serier:	Nature Communications
Online adgang:	https://doi.org/10.1038/s41467-025-63725-3
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