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The impact of kidney dysfunction on blood-brain barrier integrity and neurological conditions

Abstract The kidney–brain axis represents a bidirectional pathophysiological link between chronic kidney disease (CKD), acute kidney injury (AKI), and blood–brain barrier (BBB) dysfunction. CKD affects over 800 million individuals globally and is associated with accelerated cognitive decline, stroke...

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Principais autores: Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Ikponmwosa Ogieuhi, Komolafe Babajide Ayodeji, Victor Oluwatomiwa Ajekiigbe, Muhammadul-Awwal Irodatullah Bisola, Joan Oluwadamilola Ajayi, Chinonyelum Agbo, Oluwatobi Omoworare, Adetola Babalola, Jonathan Oluwafemi Adeola, Israel Charles Abraham
Format: Artigo
Sprog:Inglês
Udgivet: SpringerOpen 2026-03-01
Serier:The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Fag:
Blood-brain barrier
Kidney disease
Neuroinflammation
Neurotoxicity
Neurological disorders
Online adgang:https://doi.org/10.1186/s41983-026-01132-1
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