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Tamoxifen and the PI3K Inhibitor: LY294002 Synergistically Induce Apoptosis and Cell Cycle Arrest in Breast Cancer MCF-7 Cells

Breast cancer is considered as one of the most aggressive types of cancer. Acquired therapeutic resistance is the major cause of chemotherapy failure in breast cancer patients. To overcome this resistance and to improve the efficacy of treatment, drug combination is employed as a promising approach...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Mohamed E. Abdallah, Mahmoud Zaki El-Readi, Mohammad Ahmad Althubiti, Riyad Adnan Almaimani, Amar Mohamed Ismail, Shakir Idris, Bassem Refaat, Waleed Hassan Almalki, Abdullatif Taha Babakr, Mohammed H. Mukhtar, Ashraf N. Abdalla, Omer Fadul Idris
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2020-07-01
Rangatū:Molecules
Ngā marau:
breast cancer
tamoxifen
LY294002
synergism
apoptosis
cell cycle
Urunga tuihono:https://www.mdpi.com/1420-3049/25/15/3355
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