Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model

N-methyl-D-aspartate receptors (NMDARs) play a critical role in synaptic signaling, and alterations in the synaptic/extrasynaptic NMDAR balance affect neuronal survival. Studies have shown enhanced extrasynaptic GluN2B-type NMDAR (2B-NMDAR) activity in striatal neurons in the YAC128 mouse model of H...

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Bibliografiske detaljer

Principais autores:	Rujun Kang, Liang Wang, Shaun S. Sanders, Kurt Zuo, Michael R. Hayden, Lynn A. Raymond
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2019-02-01
Serier:	Frontiers in Synaptic Neuroscience
Fag:	Huntington disease (HD) NMDAR palmitoylation palmitoyl acyltransferase (PAT) huntingtin interacting protein 14 (HIP14) huntingtin interacting protein 14-like (HIP14L)
Online adgang:	https://www.frontiersin.org/article/10.3389/fnsyn.2019.00003/full
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