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Novel and recurrent BRCA1/BRCA2 germline mutations in patients with breast/ovarian cancer: a series from the south of Tunisia

Abstract Background The incidence of breast cancer (BC) and/or ovarian cancer (OC) is increasing in Tunisia especially in young women and mostly those with family history. However, the spectrum of BRCA mutations remains little explored in Tunisian patients in particular in the southern region. Metho...

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Hoofdauteurs: Dorra Ben Ayed-Guerfali, Wala Ben Kridis-Rejab, Nihel Ammous-Boukhris, Wajdi Ayadi, Slim Charfi, Afef Khanfir, Tahia Sellami-Boudawara, Mounir Frikha, Jamel Daoud, Raja Mokdad-Gargouri
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2021-03-01
Reeks:Journal of Translational Medicine
Onderwerpen:
Breast cancer
Ovarian cancer
BRCA1
BRCA2
Germline mutation
Genetic testing
Online toegang:https://doi.org/10.1186/s12967-021-02772-y
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