Invasion of Dendritic Cells, Macrophages and Neutrophils by the Bordetella Adenylate Cyclase Toxin: A Subversive Move to Fool Host Immunity

Adenylate cyclase toxin (CyaA) is released in the course of B. pertussis infection in the host’s respiratory tract in order to suppress its early innate and subsequent adaptive immune defense. CD11b-expressing dendritic cells (DC), macrophages and neutrophils are professional phagocytes and key play...

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Detalhes bibliográficos

Principais autores:	Giorgio Fedele, Ilaria Schiavoni, Irena Adkins, Nela Klimova, Peter Sebo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-09-01
Colecção:	Toxins
Assuntos:	immune response intracellular pathways phagocytosis T-helper cells
Acesso em linha:	https://www.mdpi.com/2072-6651/9/10/293
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