Genetic engineering of Escherichia coli to improve L-phenylalanine production

Abstract Background L-phenylalanine (L-Phe) is an essential amino acid for mammals and applications expand into human health and nutritional products. In this study, a system level engineering was conducted to enhance L-Phe biosynthesis in Escherichia coli. Results We inactivated the PTS system and...

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Auteurs principaux:	Yongfei Liu, Yiran Xu, Dongqin Ding, Jianping Wen, Beiwei Zhu, Dawei Zhang
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2018-01-01
Collection:	BMC Biotechnology
Sujets:	L-phenylalanine Metabolic engineering Proteomics TyrR AroD
Accès en ligne:	http://link.springer.com/article/10.1186/s12896-018-0418-1
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