A cytotoxic-skewed immune set point predicts low neutralizing antibody levels after Zika virus infection

Summary: Although generating high neutralizing antibody levels is a key component of protective immunity after acute viral infection or vaccination, little is known about why some individuals generate high versus low neutralizing antibody titers. Here, we leverage the high-dimensional single-cell pr...

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Principais autores:	Elizabeth E. McCarthy, Pamela M. Odorizzi, Emma Lutz, Carolyn P. Smullin, Iliana Tenvooren, Mars Stone, Graham Simmons, Peter W. Hunt, Margaret E. Feeney, Philip J. Norris, Michael P. Busch, Matthew H. Spitzer, Rachel L. Rutishauser
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-05-01
coleção:	Cell Reports
Assuntos:	CP: Immunology
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124722005861
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