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Venetoclax plus low-intensity chemotherapy for adults with acute lymphoblastic leukemia

Abstract: In acute lymphoblastic leukemia (ALL), the B-cell lymphoma 2 inhibitor venetoclax may enhance the efficacy of chemotherapy, allowing dose reductions. This phase 1b study of venetoclax plus attenuated chemotherapy enrolled 19 patients with ALL either newly diagnosed (aged ≥60 years, n = 11...

Deskribapen osoa

Gorde:
Egile Nagusiak: Marlise R. Luskin, Shai Shimony, Julia Keating, Eric S. Winer, Jacqueline S. Garcia, Richard M. Stone, Elias Jabbour, Yael Flamand, Kristen Stevenson, Jeremy Ryan, Zhihong Zeng, Anthony Letai, Marina Konopleva, Nitin Jain, Daniel J. DeAngelo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2025-02-01
Saila:Blood Advances
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2473952924006554
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