Highly pathogenic avian influenza virus H5N1 controls type I IFN induction in chicken macrophage HD-11 cells: a polygenic trait that involves NS1 and the polymerase complex

<p>Abstract</p> <p>Background</p> <p>Influenza A viruses are well characterized to antagonize type I IFN induction in infected mammalian cells. However, limited information is available for avian cells. It was hypothesised that avian influenza viruses (AIV) with distinct virulence may interact diffe...

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Bibliografische Detailangaben

Hauptverfasser:	Liniger Matthias, Moulin Hervé R, Sakoda Yoshihiro, Ruggli Nicolas, Summerfield Artur
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2012-01-01
Schriftenreihe:	Virology Journal
Schlagworte:	H5N1 avian influenza A virus chicken HD-11 macrophage-like cell line type I interferon nonstructural protein 1 viral polymerase complex
Online-Zugang:	http://www.virologyj.com/content/9/1/7
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