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Durable responses to long-term selumetinib in Chinese pediatric NF1 patients with inoperable plexiform neurofibromas

BackgroundThis study provides the first long-term efficacy and safety data of selumetinib in Chinese pediatric patients with inoperable symptomatic plexiform neurofibromas (PN) associated with neurofibromatosis type 1 (NF1).MethodsIn this single-center Phase I clinical trial(NCT04590235), we enrolle...

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Bibliografiske detaljer
Principais autores: Xin Zhang, Wenyuan Sui, Hui Zheng, Jihui Chen, Xiaojun Yuan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:Frontiers in Pharmacology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2026.1855171/full
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