The protective role of tacrine and donepezil in the retina of acetylcholinesterase knockout mice

<b>AIM:</b>To determine the effect of different concentrations of the acetylcholinesterase (AChE) inhibitors tacrine and donepezil on retinal protection in AChE^+/- mice (AChE knockout mice) of various ages.<b>METHODS:</b>Cultured ARPE-19 cells were treated with hydrogen peroxide (H2O2) at...

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Detalhes bibliográficos

Principais autores:	Yun-Min Yi, Li Cai, Yi Shao, Man Xu, Jing-Lin Yi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Press of International Journal of Ophthalmology (IJO PRESS) 2015-10-01
coleção:	International Journal of Ophthalmology
Assuntos:	retinal pigment epithelium acetylcholinesterase apoptosis AChE<sup>+/- </sup>animal models acetylcholinesterase inhibitors
Acesso em linha:	http://www.ijo.cn/en_publish/2015/5/20150506.pdf
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