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White matter differences between healthy young ApoE4 carriers and non-carriers identified with tractography and support vector machines.

The apolipoprotein E4 (ApoE4) is an established risk factor for Alzheimer's disease (AD). Previous work has shown that this allele is associated with functional (fMRI) changes as well structural grey matter (GM) changes in healthy young, middle-aged and older subjects. Here, we assess the diffusion...

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Detalhes bibliográficos
Principais autores: Laurence O'Dwyer, Franck Lamberton, Silke Matura, Monika Scheibe, Julia Miller, Dan Rujescu, David Prvulovic, Harald Hampel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2012-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3338494?pdf=render
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