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Etiological diagnosis of miscarriage by combining use of chromosomal microarray analysis and whole-exome sequencing

Abstract Background Chromosomal microarray analysis (CMA) is being increasingly used to reveal the genetic causes of miscarriage. Nevertheless, approximately half of the time it cannot produce a clear diagnosis. This study aims to investigate the genetic etiology of miscarriage by combining the use...

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Principais autores: Jianlong Zhuang, Wanyu Fu, Ling Gu, Xiaofang Ye, Junyu Wang, Chunnuan Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-07-01
Serier:European Journal of Medical Research
Fag:
Chromosomal microarray analysis
Whole-exome sequencing
Etiological diagnosis
Miscarriage
Molecular diagnosis
Online adgang:https://doi.org/10.1186/s40001-025-02709-x
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