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Thioredoxin, produced by stromal cells retrieved from the lymph node microenvironment, rescues chronic lymphocytic leukemia cells from apoptosis in vitro

Background and Objectives The redox-regulatory protein thioredoxin has several functions including transcriptional regulation, and antioxidant, cytokine, and chemokine activities. We have previously shown that extracellular thioredoxin protects B-cell chronic lymphocytic leukemia (CLL) cells from ap...

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Autors principals: Eva Bäckman, Ann-Charlotte Bergh, Irena Lagerdahl, Björn Rydberg, Christer Sundström, Gerard Tobin, Richard Rosenquist, Mats Linderholm, Anders Rosén
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2007-11-01
Col·lecció:Haematologica
Accés en línia:https://haematologica.org/article/view/4630
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