Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges

Abstract Mass spectrometry (MS)-based intact mass analysis and structural characterization of biotherapeutic proteins such as monoclonal antibodies (mAbs) are a crucial characterization approach from upstream drug development to downstream product analysis. Due to various endogenous modifications le...

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Ngā taipitopito rārangi puna kōrero

Ngā kaituhi matua:	Abhik Mojumdar, Hee-Jin Yoo, Duck-Hyun Kim, Jiwon Park, Su-Jin Park, Eunji Jeon, Sunhee Choi, Jung Hoon Choi, Moonhee Park, Geul Bang, Kun Cho
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	SpringerOpen 2024-04-01
Rangatū:	Journal of Analytical Science and Technology
Ngā marau:	Monoclonal antibody Native Top down High throughput Mass spectrometry
Urunga tuihono:	https://doi.org/10.1186/s40543-024-00437-1
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!