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Factor-inhibiting HIF (FIH) promotes lung cancer progression

Factor-inhibiting HIF (FIH) is an asparagine hydroxylase that acts on hypoxia-inducible factors (HIFs) to control cellular adaptation to hypoxia. FIH is expressed in several tumor types, but its impact in tumor progression remains largely unexplored. We observed that FIH was expressed on human lung...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ana García-del Río, Endika Prieto-Fernández, Leire Egia-Mendikute, Asier Antoñana-Vildosola, Borja Jimenez-Lasheras, So Young Lee, Adrián Barreira-Manrique, Samanta Romina Zanetti, Ander de Blas, Paloma Velasco-Beltrán, Alexandre Bosch, Ana M. Aransay, Asis Palazon
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical investigation 2023-10-01
Schriftenreihe:JCI Insight
Schlagworte:
Cell biology
Online-Zugang:https://doi.org/10.1172/jci.insight.167394
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