Identifying metabolic bottlenecks for micafungin precursor production via untargeted regulatory perturbation
Abstract Background Micafungin, a clinically important echinocandin antifungal agent, is derived from the nonribosomal cyclic hexapeptide FR901379 produced by the filamentous fungus Coleophoma empetri. However, low fermentation efficiency remains a major constraint in its industrial production. Resu...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2026-01-01
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| Seria: | Biotechnology for Biofuels and Bioproducts |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s13068-026-02737-7 |
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