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Computational analysis of genes with lethal knockout phenotype and prediction of essential genes in archaea

ABSTRACT The identification of microbial genes essential for survival as those with lethal knockout phenotype (LKP) is a common strategy for functional interrogation of genomes. However, interpretation of the LKP is complicated because a substantial fraction of the genes with this phenotype remains...

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Detaylı Bibliyografya
Asıl Yazarlar: Kira S. Makarova, Changyi Zhang, Yuri I. Wolf, Svetlana Karamycheva, Rachel J. Whitaker, Eugene V. Koonin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2024-02-01
Seri Bilgileri:mBio
Konular:
Online Erişim:https://journals.asm.org/doi/10.1128/mbio.03092-23
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