CD133 Stimulates Cell Proliferation via the Upregulation of Amphiregulin in Melanoma

CD133, a cancer stem cell (CSC) marker in tumors, including melanoma, is associated with tumor recurrence, chemoresistance, and metastasis. Patient-derived melanoma cell lines were transduced with a Tet-on vector expressing CD133, generating doxycycline (Dox)-inducible cell lines. Cells were exposed...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Cynthia M Simbulan-Rosenthal, Nusrat Islam, Yogameenakshi Haribabu, Ryyan Alobaidi, Azadeh Shalamzari, Garrett Graham, Li-Wei Kuo, Peter Sykora, Dean S Rosenthal
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2024-05-01
Цуврал:	Cells
Нөхцлүүд:	melanoma initiating cells melanoma stem cells CD133 AREG EGFR MAPK pathway
Онлайн хандалт:	https://www.mdpi.com/2073-4409/13/9/777
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!