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Infiltrating macrophages and interferon gamma rather than renal genotype dictate heightened crescentic glomerulonephritis

BackgroundBoth intrinsic renal cells and immune cells contribute to driving renal inflammation and damage. However, the respective roles of intrinsic renal cells and immune cells in crescentic glomerulonephritis, and the key molecular factors driving pathogenesis are still unclear.MethodsThe roles o...

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Principais autores: Yong Du, Yuyang Fu, Yuyang Gao, Dugyala Poojitha, Vanarsa Kamala, Quanzhen Li, Xinjing Zhou, Chandra Mohan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2024-12-01
coleção:Frontiers in Immunology
Assuntos:
macrophage
interferon-gamma
crescentic glomerulonephritis
intrinsic renal cells
renal transplant
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1484525/full
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