Identifying key multi-modal predictors of incipient dementia in Parkinson’s disease: a machine learning analysis and Tree SHAP interpretation

BackgroundPersons with Parkinson’s disease (PD) differentially progress to cognitive impairment and dementia. With a 3-year longitudinal sample of initially non-demented PD patients measured on multiple dementia risk factors, we demonstrate that machine learning classifier algorithms can be combined...

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Autors principals:	G. Peggy McFall, Linzy Bohn, Myrlene Gee, Shannon M. Drouin, Harrison Fah, Wei Han, Liang Li, Richard Camicioli, Roger A. Dixon
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-06-01
Col·lecció:	Frontiers in Aging Neuroscience
Matèries:	Parkinson’s disease dementia risk factors biomarkers random forest classifier Tree SHapley Additive exPlanation
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fnagi.2023.1124232/full
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