Association between cholinesterase activity and critical illness brain dysfunction

Abstract Background Delirium is a frequent manifestation of acute brain dysfunction and is associated with cognitive impairment. The hypothesized mechanism of brain dysfunction during critical illness is centered on neuroinflammation, regulated in part by the cholinergic system. Point-of-care serum...

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Principais autores:	Christopher G. Hughes, Christina S. Boncyk, Benjamin Fedeles, Pratik P. Pandharipande, Wencong Chen, Mayur B. Patel, Nathan E. Brummel, James C. Jackson, Rameela Raman, E. Wesley Ely, Timothy D. Girard
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-12-01
coleção:	Critical Care
Assuntos:	Acetylcholinesterase Butyrylcholinesterase Delirium Cognitive impairment Critical illness
Acesso em linha:	https://doi.org/10.1186/s13054-022-04260-1
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