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Use of the liquisolid compact technique for improvement of the dissolution rate of valsartan

The aim of this study was to improve the dissolution rate of the poorly soluble drug valsartan by delivering the drug as a liquisolid compact. Liquisolid compacts were prepared using propylene glycol as solvent, Avicel PH102 as carrier, and Aerosil 200 as the coating material. The crystallinity of t...

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Principais autores: Naveen Chella, Nalini Shastri, Rama Rao Tadikonda
格式: Artigo
語言:Inglês
出版: Elsevier 2012-10-01
叢編:Acta Pharmaceutica Sinica B
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在線閱讀:http://www.sciencedirect.com/science/article/pii/S2211383512001165
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