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Assessment of causality association between serum adiponectin levels and the risk of Alzheimer’s disease and Parkinson’s disease: a Mendelian randomization study

BackgroundUntil recently, the association between circulating adiponectin (ADPN) levels and the risk of Alzheimer’s disease (AD) and Parkinson’s disease (PD) remained unclear.MethodsWe utilized public data from the IEU GWAS database to conduct a two-sample bidirectional Mendelian randomization (MR)...

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Principais autores: Jiali Lin, Langhuan Lei, Qiuyu Liang, Xiaozhi Huang, Yanping Ding, Liuxian Pan, Jianrong Yang, Wei Li
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-04-01
Serier:Frontiers in Neurology
Fag:
adiponectin
Alzheimer’s disease
Parkinson’s disease
Mendelian randomization
neurodegenerative diseases
Online adgang:https://www.frontiersin.org/articles/10.3389/fneur.2025.1395798/full
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