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Suppression of hyperexcitability of trigeminal nociceptive neurons associated with inflammatory hyperalgesia following systemic administration of lutein via inhibition of cyclooxygenase-2 cascade signaling

Abstract Introduction Lutein is a dietary constituent known to inhibit inflammation; however, its effect on nociceptive neuron-associated hyperalgesia remains to be determined. The present study therefore investigated under in vivo conditions whether administration of lutein attenuates the inflammat...

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Principais autores: Yumiko Syoji, Ryota Kobayashi, Nako Miyamura, Tsukasa Hirohara, Yoshiko Kubota, Nobuo Uotsu, Kei Yui, Yoshihito Shimazu, Mamoru Takeda
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-11-01
Serier:Journal of Inflammation
Fag:
Inflammation
Edema, lutein
Trigeminal nociceptive neuron
Hyperalgesia
Single-unit recording, cyclooxygenase-2
Online adgang:http://link.springer.com/article/10.1186/s12950-018-0200-0
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